Özet:

Endometrial receptivity is a temporary process with the functional success of the endometrium epithelium. In this study, the endometrium tissues of individuals with fertile and Repeated Implantation Failure (TIB) were assessed in an immune-histochemical perspective with the Transmission Electron Microscope (TEM) and E-Caderin. Our goal is not only to compare the endometrium tissues of women with fertile and TB, but also to ensure a better understanding of the cell roof and mechanics of the implantation process in the endometrium. Tools and methods: In vitro fertilization (IVF) / Embryo Transfer (ET) for our research has been included in our study of seven infertile and ten fertile women who do not develop pregnancy. Routine light microscope and TEM techniques provide tissue tracking. The findings: In the endometrium surface epithelium of the fertile group, the formation of the pinopod indicator of implantation is widely observed, while in the infertile group, the insufficient formation of the pinopod and the manifest presence of silia and microvillus are observed. Immunohistochemic studies with E-Caderin have been scored. While immune reactiveness in the fertile group epithelium is very uncertain, there has been a more noticeable color in the infertile group. Results: The latest findings are that E-caderine’s transmission of endometrial epithelial adhesive properties in the receptive period, as well as having a binary function. In the early stages, it is believed that it provides adhesion on the cell surface, then separates in the epithelial cells and is suppressed to activate the invasion of the blastosist. In this study, unlike the TB group, it is important for the fertile group epithelium to facilitate very weak painting, blastosist implantation.

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