Özet:

Purpose: The purpose of this study is to investigate the prognostic importance of extracapsular invasion in stomach cancer and the relationship with clinic pathological data. Patients and Method: A total of 190 primary stomach cancer patients with total and subtotal gastrectomy between 2013 and 2020 were included in the study. 133 of the patients (70%) were male and 57 (30%) female. Detection of the invasion of tumor cells outside the metastatic lymphatic nod capsule was defined as extracapsular invasion and, in addition, histological type, lymphatic nod positive, lymphovascular and perinoral invasion, invasion depth and metastatic lymphatic nod numbers were evaluated. Results: 136 (71.4) patients had lymphatic nod metastases. In 87 of them (64%) extracapsular invasion was followed. 36 of the extracapsular invasive incidents (65,5%) were differentiated, 51 (63) and 68 (68) and 80 (68,4) respectively perinoral - lymphovascular invasions. A statistically meaningful relationship was observed between perinoral invasion (p=0.01), lymphovascular invasion (p=0.008), the depth of invasion (p=0.001) and the number of metastatic lymph nodes (p=0.001) and extracapsular invasion. Extrakapsular invasion was not associated with gender, histological type and type of resection. In multi-variable analysis, the risk of extracapsular invasion in infected tumors of the stomach cardiac was 5,501 times higher, while in perinoral invasion, the risk of extracapsular invasion was 1,44 times higher. The result: cases of extracapsular invasion are associated with poor prognostic parameters. The state of extracapsular invasion of stomach cancers should be included in the future evolution system and the pathological reports should include information about the state of extracapsular invasion.