Özet:

Antipsychotics have been used for many years in the treatment of various psychiatric disorders such as schizophrenia and bipolar disorder. Dystonia, tardive dyskinesia, akathisia, sedation, weight gain, arrhythmia are some of the side effects of antipsychotics. Peripheral edema is another important side effect of antipsychotics. Peripheral edema, which can be defined as the presence of more fluid than normally required in the interstitial space, has been reported to be associated with both first-generation antipsychotics and second-generation antipsychotics. Supersensitivity and vasodilation, dose-response relationship, rate of dose escalation and allergic reaction models have been created to explain the possible mechanisms of this side effect. The differential diagnosis of this side effect, which impairs patient comfort, and determination of possible risk factors is important. These patients should be handled with a multidisciplinary approach and should not be late in the intervention. Patients and their relatives should be warned against this side effect.

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