Abstract:

We aimed at comparing the effects of propofol and dexmedetomidine sedation on eye pressure in cases of regional anesthesia and oftalmic non-chirurgical surgery. Planned sedation application along with the axil plexus block, the 60 ellective hand surgical phenomenon was randomized into two groups. In group P (n=30) propofol, 1mg kg-1 iv in 10 minutes after the load dose, Ramsay Sedation Score (RSS) 3-4 was continued to 50-100 μg kg-1dk-1 iv infusion. For incidents in Group D (n=30) dexmedetomidine was continued to the infusion of 0.2-0.7 μg kg-1sa-1 so that 1 μg kg-1sa-1 iv 10 minutes after charge dosage would be RSS 3-4 . Eye-in-air pressure, work medication load dosage before (control value) and after, 15 and 30 of the operation. In minutes, at the end of the operation, "Tonopen XL was measured with the applanation tonometer. Propofol dropped an average dose of 18.6 per cent in the 15th minute, 17.8 per cent in the 30th minute, 21.7 per cent in the 30th minute, and 13.3 per cent in the end of the operation. Dexmedetomidine dropped by 34.1 per cent in the 15th minute, 36.4 per cent in the 30th minute, 42.1 per cent in the 30th minute and 40.1 per cent in the end of the operation. When compared groups with each other, it was found that the rates of reduction of eye pressure according to the control value were statistically meaningful (p<0.05). In cases of nausea, vomiting, allergy, hypotension, bradykardi and apnea were not observed. Propofol and dexmedetomidine are sedative agents that can be used safely in ophthalmic surgery. In addition to the similar hemodynamic effects of sedation levels, dexmedetomidine can be preferred in the first place because it reduces the intraocular pressure further.

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