Background:Breast cancer is the most common and deadly malignancy of women globally. Breast cancer is called ER/PR positive if it has receptors for hormone estrogen/progesterone. Similarly HER2neu positive status of breast carcinoma means that HER2neu gene is making too many HER2neu proteins. Hormone receptor studies with ER, PR & HER2neu are routinely done in breast carcinoma. Ki67 is an independent factor to predict tumour grade. Breast carcinoma can therefore be classified based on expression patterns of ER, PR, HER2neu & correlated with Ki67 into various molecular subtypes.
Alan : Sosyal, Beşeri ve İdari Bilimler
Dergi Türü : Uluslararası
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