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Evaluation of the Relationship Between Transcutaneous Bilirubin Measurement and Total Serum Bilirubin in Neonatal Patients Followed for Jaundice
2021
Journal:  
Şişli Etfal Hastanesi Tıp Bülteni
Author:  
Abstract:

Objectives: Jaundice is a physiological condition caused by hyperbilirubinemia, which is common in neonatal period. However, severe hyperbilirubinemia can cause kernicterus, which is a serious condition that leads to neurological problems. In this study, we aimed to investigate whether it is safe to use transcutaneous bilirubin (TcB) instead of blood for the evaluation of jaundice by comparing TcB measurement with standard total serum bilirubin (TSB) measurement values. Methods: A total of 105 term and early term infants with gestational ages between 37 and 42 weeks were included in the study. MBJ20 TcB measuring device was used for TcB measurement. TcB was measured from the forehead and sternum. To evaluate the relationship between TcB measurements and TSB measurements, we performed Pearson correlation, Spearman correlation, linear regression analysis, and Bland-Altman analysis in which we evaluated the scatter plot of the differences between the average values of the measurements. Results: There was a positive and statistically significant correlation between TcB forehead and TSB measurements and TcB sternum and TSB measurements (p<0.001). Linear regression analysis showed a positive directional correlation between TcB forehead and TSB measurements (R²=0.85) and TcB sternum and TSB measurements (R²=0.87). Bland-Altman analysis showed a good consistency between TSB and TcB forehead measurement methods (mean difference: 0.39±1.46, 95% CI: [−2.47]–[3.26]), and between TSB and TcB sternum measurement methods (mean difference: 0.49±1.32 95% CI: [−2.1]–[3.07]). Conclusion: As a result of our study, we found that TcB measurement can be reliable instead of taking blood for jaundice evaluation.

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Assessment of the relationship between transcutaneous bilirubin measurement and total serum bilirubin in newborn patients followed by yellowness
2021
Author:  
Abstract:

Goal: Yellowness is a physiological condition caused by the common hyperbilirubinemia in the newborn period. But when not followed and treated, serious hyperbilirubinemia can cause kernicterosis, a serious condition that leads to neurological problems. In our study, we aimed to investigate whether it would be safe to use the TcB measurement instead of taking blood for yellow assessment by comparing the total serum bilirubin (TSB) measurement values, which is the standard method of transcutan bilirubin (TcB) measurement. MATERIAL AND METHOD: 105 babies were taken to study with gestational ages between 37 and 42 weeks. In TcB measurement, the MBJ20 transcutaneous bilirubin measurement device was used. TcB measurement was made from the sternum and the sternum. To evaluate the relationship between TcB measurements and TSB measurements, we implemented the Bland-Altman analysis, which we assessed the differences between pearson correlation, Spearman correlation, linear regression analysis and average measurements. Results: TcB take and there was a very good level and statistically meaningful correlation in the positive direction between TSB measurements and TcB sternum and TSB measurements (p<0.001). Linear regression analysis found that there was a linear relationship between TSB measurements (R2=0.85) and TcB sternum and TSB measurements (R2=0.87) (+). TSB and TcB take measurement methods (medial difference: 0.39±1.46, 95% CI: (-2.47)-(3.26)) and between TSB and TcB sternum measurement methods (medial difference: 0.49±1.32% 95 CI: (-2.1)-(3. In Bland-Altman analysis, we found a good harmony between the two methods. As a result of our study, we found that TcB measurement can be used safely instead of taking blood for yellowness assessment. (SETB 2020-01-08)

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2021
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Şişli Etfal Hastanesi Tıp Bülteni

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

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Şişli Etfal Hastanesi Tıp Bülteni