Objective: Helicobacter pylori (H. pylori) is a Gram-negative microaerophilic bacterium that is associated with diseases such as peptic ulcer, chronic gastritis, gastric MALT lymphoma, and gastric cancer. H. pylori infection is more common in developing countries. The high socioeconomic conditions and elimination of bacterial carriage by antimicrobial treatment reduce the prevalence of H. pylori in developed countries. The fecal H. pylori antigen test has been widely used recently. This test with high sensitivity and specificity constitutes a significant diagnostic method alternative due to its cost-effectiveness and rapid results. In this study, we retrospectively analyzed the presence of H. pylori antigen in the stool samples of patients with gastroduodenal complaints from laboratory records. Methods: Test results of patients who underwent H. pylori antigen rapid cassette test from fresh fecal samples between January 2018 and May 2022 in the Medical Microbiology Laboratory were included in the study. Fresh fecal samples from patients were analyzed using H. pylori Antigen Rapid Test Cassette (Acro Biotech Inc, USA) kits. The statistical analysis of the research was made with IBM-SPSS 25.0 (IBM Co., USA). The chi-square test was used to evaluate the research data. P<0.05 value was considered statistically significant. Results: A total of 5,718 patients, 3,285 (57.5%) women with gastroduodenal complaints, were included in the study. Fecal H. pylori antigen test positivity was determined in 1,429 (25%) of these patients. The antigen positivity rate was found to be higher in women (26.6%) compared to men (22.9%) (p<0.05). In addition, this rate was higher in adult patients (27.4%) than in pediatric patients (10.1%). In addition, this rate was higher in adult patients (27.4%) compared with pediatric patients (10.1%) (p<0.01). Conclusion: The regional prevalence data are informative about the development levels of countries in socioeconomic issues such as urbanization, infrastructure services, and access to clean water. In addition, these data may provide insight into the future prevalence of H. pylori-related diseases. We think that this study, in which the data of our region is shared, contributes to the literature.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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