Abstract:

Purpose: cardiovascular events, including ventricular arithms and sudden heart death (CER) in patients with hemodialysis (HD), are the primary source of death. Control of ECG parameters such as QT range, QT dispersion (QTd), TPe range, TPe / QT ratio and cardiovascular-electrophysical balance (iCEB = QT / QRS) can be useful in classification of patients with high arithmia and SCD risk. Our study aimed at comparing the change in electrocardiographic parameters before and after the HD session with a healthy control group. Methods: The study included 49 HD patients and 50 healthy volunteers. The groups were divided into two groups as a hemodialysis and control group. The ECGs of the hemodial group were assessed before and after the dialyse. The ECG data was scanned and evaluated on a digital platform. QT, cQT, QTd, TPe, TPe / QT, TPe / cQT, QT / QRS and cQT / QRS were measured. Results: After hemodialysis QTd, cQTd, TPe, TPe / QTc and QRS significantly decreased compared to pre-HD (p <0,05 for each), after dialytic treatment HR, iCEB and iCEBc showed significant increase (p <0,05 for each). When compared with pre-dialytic ECG parameters, the control group was significantly higher in QT, cQT, QTd, cQTd, TPe and iCEBc pre-HD (p <0.05 for each). When compared with post-dialytic ECG parameters, the HR, cQT, QTd, cQTd, iCEB and iCEBc values were significantly higher according to the control group (p <0.05 for each). The result: by assessing the electrocardiographic parameters indicating ventricular repolarization and depolarization together in HD patients, the risk of arithmia and sudden heart death can be predicted.