Özet:

Full cereal nutrients are considered as nutrients with health protective effects due to the dietary poses, minerals, vitamins and phytochemicals found in their composition. Alkilresorsinol compounds, which are found in the structure of whole grains and are an amphiphylic phenolic lipide, have been a topic focused on in recent years. Specifically in vitro studies indicate that alkilresorsinols have a variety of physiological and biological activities, such as antimicrobial, antioxidant, membrane phospholipite activity and enzyme activity and tumorogenesis inhibition. The phenolic circle and alkyl chain found in the structure of alkylresinols is indicated to be important in order to prevent the reproduction of human cancer cells. Studies have shown that alkylresorsinols may have an important role in cancer pathogenesis with the ability to inhibit and influence genotoxicity of certain enzymes, antioxidant activity and cytotoxic effects on cancer cell lines. It is stated that high concentrations of alkylresorsinols provide the inhibition of human colon, breast, lungs, over, prostate and liver cancer cell lines and are considered to be high cytotoxic agents for these cancers. It is also believed that alkylresorsinols have an important mechanism in the prevention of testosterone and estradiol-dependent cancers by influencing the synthesis of sex hormones. However, there is no sufficient evidence of the relationship of alkilresorsinols with the risk of cancer. With future studies, the creation of secure concentrations and acceptable daily intake amounts for alkilresorsinols will provide clearer information. However, the potential role of alkylresorsinols in the development of cancer is to support public health recommendations that emphasize that a diet rich in whole grains is potentially protective against some types of cancer. This collection aims to study the role of alkilresorsinols in cancer pathogenesis and to illuminate the relationship between alkilresorsinols and cancer.

Anahtar Kelimeler: