Abstract:

Background and Aims: Serious complications have been with endoscopic retrograde cholangiopancreatography, a widely used method for the diagnosis and treatment of even duct and pancreatic diseases. These complications include hemorrhage from the sphincterotomy site due to the endoscopic retrograde cholangiopancreatography procedure; pancreatitis; cholangitis; cardiopulmonary complications such as perforation, hypoxia, and hypotension, arrhythmia; and death. Our aim in this study is to determine the risk factors in patients with complications of the endoscopic retrograde cholangiopancreatography procedure and to determine the appropriate diagnostic and therapeutic approach in these patients. Materials and Methods: Data on 487 patients undergoing endoscopic retrograde cholangiopancreatography in 2016 were retrospectively reviewed. Results: A total of 487 patients underwent endoscopic retrograde cholangiopancreatography, 304 (62.4%) women and 183 (37.6%) men. The average age was 61.53 (range: 18-99) years. Post-endoscopic retrograde cholangiopancreatography complications occurred in 53 (10.8%) patients; 37 (7.6%) pancreatitis; 15 (3.1%), bleeding; and 1 (0.2%), duodenal perforation. Post-endoscopic retrograde cholangiopancreatography improved in 2/67 (2.9%) cases with needle knife pre-cut sphincterotomy and did not develop in cases of standard sphincterotomy 65/420 (8.33%). Post-endoscopic retrograde cholangiopancreatography was less frequent in pre-cut sphincterotomy constructs, but the difference was not statistically significant (p=0.127). When the number of endoscopic retrograde cholangiopancreatography and post-ERCP cases who developed pancreatitis was compared, post-endoscopic retrograde cholangiopancreatography pancreatitis was significantly more frequent for the first time endoscopic retrograde cholangiopancreatography applied (91%) (p=0.041). Mortality was not observed in post-ERCP pancreatitis. Conclusion: Post-endoscopic retrograde cholangiopancreatography is the most common complication of endoscopic retrograde cholangiopancreatography. Although serious complications can be seen with endoscopic retrograde cholangiopancreatography, the technique should be used with the appropriate indications, and early identification of complications is the most important step in preventing morbidity and mortality.