We studied anticardiolipin antibody isotypes and VDRL in 45 systemic lupus erythematosus (SLE) patients. These patients were also screened for some other autoantibodies, such as anti-DNA, antimitochondrial (AMA) type 5 and antinuclear antibodies. Out of 45 patients, 55.5% were anticardiolipin (ACL) antibody positive. IgG class ACL antibodies were mainly detected in patients having thrombotic events and fetal losses. IgM class ACL antibody positivity was only associated with fetal losses. We also found a significant correlation between the presence of AMA type 5 and VDRL positivity with ACL-IgG and ACL-IgM antibodies.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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