Özet:

The purpose of this study is to evaluate the contribution of diffusion weighted MRI and measured ADC values in patients who have primary lung tumor with brain metastasis. Methods: 91 patients with mean age of 59.35±9.364 (19 females,72 males) admitted Istanbul Training and Research Hospital, Radiology Clinic between the dates 2009 to 2011, with the diagnosis of primary lung cancer, were included in the study. In addition to conventional MRI sequences, b-value 1000 s/mm² with the DWI was performed using the SE-EPI sequence. The patients were retrospectively evaluated by using picture archiving and communication system (PACS). DWI and ADC images were evaluated qualitatively and quantitatively. RESULTS: When we assess the metastatic lesions in 91 patients according to their localities we have seen the most metastatic lesions in frontal lobe (in 28 patients) and the most metastatic lesions in were white matter (in 40 patients). In DWI and ADC sequence qualitative assessment we found hiperintensity in most of metastatic lesions. In quantitative assessment according to DWI and ADC value comparisons between the groups there was no significant statistical difference between the groups (p>0.05), but there was significant statistical difference between metastatic lesions and normal brain parenchyma (p<0.05). Conclusion: Although some of our cases show restricted diffusion like some primary brain masses there is a high varieity of signal intensity in DWI for all of them. For this reason we can not differentiate metastatic brain tumors with only visual assessment in DWI or ADC. DAG-ADC with quantitative measurement can distinguish metastatic lesions from normal brain parenchyma. We couldn’t define any correlation between DWI/ADC values and primary histology of the metastatic foci. We believe that more accurate results can be achieved with advanced studies with more patients included and a common sequence features.

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