Özet:

Purpose: In this placebo-controlled, prospective, randomized, single-blind study, the aim is to compare the effects of esmolol and fentanyl on the hemodynamic response in the traceal entubation. Method: ASA I-II group between 18-65 years of age 90 facts were taken to study in three groups (n=30). The first group was given 150 mg esmolol (Group E), the second group 1.5 μg/kg fentanyl (Group F), and the third group 4 cc serum physiological (SF) (Group K) intravenously (iv). Induction was done with 2 mg/kg propofol and 0.6 mg/kg rocuronyum. Patients' systolic, diastolic, average arterial pressure and heart rate were measured and recorded in 1, 2, 3, 5, 7, 9 and 11 minutes before induction, after induction, before entubation, after entubation. Results: In group comparison, the increase in post-entubation heart rate was found low in Group E in 1, 2, 3 and 5 minutes compared to Group F and Group K (p0.05). The result: Although esmolol fentanyl was better in preventing increases in post-entubation heart rate than esmolol fentanyl in preventing increases in blood pressure, both agents given alone in preventing increases in blood pressure were not sufficient.