Özet:

Purpose: Invasive surgical trials that cause acute stress can lead to immune and hormonal changes in patients. In previous studies, crown bypass, myocardial infarction, increased serum prostate specific antigen (PSA) levels. Our study aims to investigate the effect of surgical stress on the serum PSA level. Methods: Our study included 33 patients who were undergoing an open kidney stone surgery and who had no infectious prostate disease or prostate cancer that would increase PSA. Pre-op and post-op patients. Day free (s-) and total (t-) PSA values, serum luteinizing hormone (LH), follicle stimulating hormone (FSH), s- and t-testosterone, C-reactive protein (CRP), erythrosite sedimentation rate, fibrinogen, albumin, ferritin levels were studied. The statistical analysis was performed using the Wilcoxon signed ranks test. The average age of patients was 53.9±8 (40-66). s- and t-PSA, all values except the LH values have changed significantly according to the basal period in the post-op period. In the endocrine response after surgery, the serum levels of acute phase reactors such as CRP, fibrinogen, ferritin and ESR are increased. But in this study, unlike the acute phase reactors, the levels of s, t-testosterone, albumin and FSH have decreased post-op. The result: Our findings show that acute surgical stress does not affect the serum PSA level. (JAREM 2015; 5: 22-4)

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