Özet:

Youth idiopathic arthritis (JIA) is the most common rheumatic disease of childhood in the world. It is not a single disease rather composed of distinct subtypes. Apart from musculoskeletal complications, uveitis is one of the major causes of morbidity in JIA. The aim of this study was to demonstrate subtype distribution and frequency of uveitis in JIA. The study was conducted in two pediatric rheumatology centers of Southeastern part of Turkey. Results: The cohort consisted of 264 children with slightly female predominance (females: 54.9%, property: 45.1%). Mean duration of follow-up was 13.8 ± 5.8 months. The most common subtype was oligoarticular JIA (42.4%) followed by enthesitis related arthritis (21.6%). The distribution of other subtypes were as follows; systemic JIA (13.6%), rheumatoid factor (RF) negative polyarticular JIA (10.2%), RF positive polyarticular JIA (9.5%), psoriatic arthritis (1.9%) and unclassified arthritis (0.8%). The frequency of uveitis was 8.7% and 91.3% of the patients with uveitis had oligoarticular JIA. Macrophage activation syndrome was observed in 13.8% of systemic JIA patients. While 18.6% of the patients had active disease at the time of registration, 81.4% had remission. DISCUSSION AND CONCLUSION: As in other parts of the world, oligoarticular JIA is the most common subtype in our country. But, in contrast to western countries, enthesitis related arthritis is the second most common subtype in Turkey. The frequency of uveitis is low in Turkish JIA children that is another major difference from the western countries and oligoarticular JIA is the most common subtype associated with uveitis. With the introduction of newer treatment modalities, remission is an achievable goal in most of the JIA patients.

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