Abstract:

Introduction and Purpose: This study aimed at the retrospective assessment of the prenatal, natal and postnatal monitoring data of mothers who had transplanted organs between 1993-2016 years and then followed due to pregnancy. In the study, 440 female patients in the reproductive age (15-49) were examined for organ transplant and followed after organ transplant in our hospital between 1993 and 2016. There were 28 studies followed after the transplant. Maternal (transplantation etiology, age, transplant age and pregnancy age, pregnancy age, time and type, the presence of assistant reproductive techniques, drugs and doses used during pregnancy) and neonatal (gravity week, birth weight, birth hall data, infants with anthropometric values low in comparison to pregnancy week (SGA), normal in comparison to pregnancy week (AGA), pregnancy week with over-born weight (LGA) infants characteristics and post-born infants with intensive care-and-mother observation status were assessed. Statistical analysis was done using the SPSS package program. Continuous variables were given an average ± standard deviation (SD). Categorical variables are expressed by frequency and percentage. The ethical committee has been approved before the research. In total, 71.4 percent of the 28 patients' organ transplant was kidney (20/28) and 28.6 percent (8/28) hepatic transplant. 60.7 percent of organ transplants (17/28) were lively transplanted, and 39.3 percent (11/28) were transplanted from the body. The most common transplant etiology was glomerulonefrite with 21.9%. 78.6 percent of pregnancies (22/28) resulted in live births and 21.4 percent (6/28) resulted in abortion. A chronic rejection was observed in one person, acute in two. The most commonly used treatment protocol is 42.9% cyclosporine + prednisolone + azatyoopurine. 40.9% of babies are therm, 40.9% SGA, and 59% are sufficient. In 4 babies (18.1%), RDS, 3 (13.6%), premature retinopathy (ROP), 1 (4.5%) NEK, 3 babies were diagnosed with congenital heart disease. 18.2% of babies needed resuscitation, while 45.4% were given to the mother after childbirth. The result: the knowledge of the results of perinatal, neonatal morbidity and mortality that arise in the follow-up of newborn babies born from pregnancies of women who have been kidney or liver transplanted in our country is important in terms of appropriate approach.

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