Özet:

In this article I.U. School of Dentistry, Dentistry. The clinical, radiological and pathological trials conducted by the Department of Chronic Diseases and Surgery and conducted by the Department of Chronic Diseases and Surgery resulted in the diagnosis of epidermoid carcinoma, keratocysts, folic cysts, and radical cysts of a total of 40 incidents studied by immunohistochemical method of the presence of the Epidermal Growth Factor Receptor (EGFR). EGFR has been observed in 90% of epidermoid carcinoma and keratocistic occurrences, 60% of follicular cyst occurrences and 50% of radical cyst occurrences. Based on these findings, we found that EGFR may have a determining characteristic of epithelial matignity. Keywords: ANIMMUNOHISTOCHEMICAL INVESTIGATION OF EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) EXPRESSION IN ODONTOGENIC CYST EPITHELIUM AND EPIDERMOID CARCINOMA OF ORAL CAVITY Abstract In this research, the patients who were applied to dental Faculty of Istanbul University, Department of Oral Surgery were evaluated and 40 cases who were diagnosed as epidermoid carcinoma, keratocyst, follicular and radicular cysts following the clinical, radiological and paffiological examination were histochemically investigated according to the presence of Epidermal Growth Factor Receptor (FREG). The EGFR presence was observed in epidermoid carcinoma and keratocysts (90%), follicles (60%), radicules (50%) cysts respectively. Based on the above results, we would like to emphasize that EGFR has a characteristic of epithelial malignancy. Key words: Epidermal Growth Factor Receptor, Odontogen Cyst, Epidermoid Carcinoma.