Özet:

Purpose: During pregnancy, metabolic and oxidative changes containing various element and oxidative stress occur. The main objective of this study was to evaluate the concentrations of zinc, copper and its oxidative status according to trimesters in normal pregnancy. Method and Method: Work 1. 30 (T1) in the trimester, 2. 30 (T2) in the trimester, 3. 30 (T3) primipar pregnancy in the trimester included 30 healthy women (Control) who were not pregnant in the same age group. Serum levels of Zinc, Copper, MDA, GPX and Catalase were looked at from all individuals. The findings: Zinc and copper continued to increase until the third three months of pregnancy, where there was a slight decline. p = 0,000 and p = 0.003 respectively. The MDA also observed irregular changes in each trimester while there was no significant change in the control and trimester in the GPX. The levels of catalase were high in the control group and the trimesters of pregnancy were high while the levels of catalase were increasing as the trimesters of pregnancy progressed. The result: the profiles of the element in the different trimesters in pregnant women have changed. A single-time measurement of the element in the serum does not seem sufficient to determine their levels during pregnancy.