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Amaç: Çalışmada, ilimizdeki çocuklarda KSÜ etiyolojisinde rol oynayabilecek faktörler ve ilişkili klinik ve laboratuvar bulguların araştırılması amaçlandı. Yöntemler: Kliniğimizde KSÜ tanısı alan 7-17 yaş arası 107 hastanın kayıtları retrospektif olarak incelendi. KSÜ’lü hastaların demografik ve klinik özellikleri, laboratuvar bulguları, atopi, enfeksiyon, otoimmüniteye yönelik tetkikleri değerlendirildi. Ek olarak hastalık şiddetinin değerlendirilmesi için Ürtiker Aktivite Skoru (ÜAS7) ve hastalık kontrolünün değerlendirilmesi için Ürtiker Kontrol Testi (ÜKT) uygulandı. Bulgular: Ortalama yaşı 11,99.2±3,34 olan 107 hasta çalışmaya dahil edildi. Hastaların %66’sına anjioödem eşlik etmekteydi. Ürtiker ortalama süresi 13,5±15,10 ay idi. Hastaların %36’sına alerjik hastalıklar eşlik etmekte idi. Hastaların %12’sinde astım ve %21’inde alerjik rinit öyküsü vardı. Olguların %33’ünde inhalen duyarlılığı ve % 6,5’inde besin alerjen duyarlılığı saptandı. %16,8’inde antinükleer antikor (ANA) pozitifliği, %6,5’inde tiroid otoantikor varlığı, %3’ünde idrar yolu enfeksiyonu, %1,9’ unda helikobakter pylori pozitifliği ve gaitada parazit tespit edildi.ÜAS7 ortalaması 12,96±9,8 ve ÜKT ortalaması 8,43±2,8 idi. ÜKT kontrollü (n=24) ve kontrolsüz (n=83) olan hastalar karşılaştırıldığında, yaş cinsiyet, anjioödem varlığı, hastalık süresi ve ANA pozitifliği açısından gruplar arasında anlamlı bir fark saptanmadı (sırasıyla, p=0,842, p=0,646, p=0,34, p=0,590, p=0,316). Sonuç: Çocuklarda KSÜ etiyolojisinde atopik hastalıklar, enfeksiyonlar, paraziter enfestasyonlar yer tutarken çoğu vakada tanı idiyopatik olarak kalmaktadır.
Purpose: The study was aimed at investigating the factors that can play a role in the ethology of the CSI in children in our province and related clinical and laboratory findings. Methods: In our clinic, the records of 107 patients between the ages of 7 and 17 who were diagnosed with KSU were retrospective. The demographic and clinical characteristics of patients with CSI, laboratory findings, atopias, infections, autoimmune examinations were evaluated. Furthermore, the Urticer Activity Score (UAS7) and the Urticer Control Test (UKT) were applied for the assessment of the severity of the disease. Results: 107 patients with an average age of 11,99.2±3,34 were included in the study. 66% of patients were accompanied by angioedema. The average duration of it was 13.5 ± 15.10 months. 36% of patients were accompanied by allergic diseases. 12% of patients had a history of asthma and 21% of patients had an allergic rinitis. In 33% of cases, inhaled sensitivity and in 6.5% nutrient allergen sensitivity were identified. 16.8 percent of anti-nuclear antibodies (ANA) positive, 6.5 percent of thyroid autoanticor presence, 3 percent of urinary infections, 1.9 percent of helicobacterial pylori positive and gaida parasites were detected. In comparison with patients with UNCT controlled (n=24) and uncontrolled (n=83) there was no significant difference between the groups in terms of age, angioedema presence, disease duration and ANA positive (respectively, p=0,842, p=0,646, p=0,34, p=0,590, p=0,316). The result: At the age of the child, atopic diseases, infections, parasitic infections are included in the etiology of the CSA, while in most cases the diagnosis remains idiopathic.
Purpose: The aim of the study was to investigate the etiology of chronic urticaria in children and the related clinical and laboratory findings in our city. Materials and methods: 107 patients aged between 7-17 years who were diagnosed with CSU in our clinic were retrospectively reviewed. Demographic and clinical characteristics were evaluated. In addition, Urticaria Activity Score (UAS) and Urticaria Control Test (UCT) were applied to evaluate disease severity. Results: A total of 107 patients with a mean age of 11.99±3.34 were evaluated. Angioedema was associated with 66% of the patients. The mean duration of urticaria was 13.5±15.10 months. Allergic diseases were associated with 36% of the patients. 12% of patients had asthma and 21% had allergic rhinitis. In 33% of cases, inhalant sensitivity and 6.5% of food sensitivity were determined. Antinuclear antibody (ANA) positivity was found in 16.8%, thyroid autoantibody was present in 6.5%, urinary tract infection was found in 3%, helicobacter pylori positivity was found in 1.9% and had positive stool examination for parasites. The mean UAS7 was 12.96±9.8 and the mean UCT was 8.43±2.8. No significant difference was found between the groups in terms of age, gender, presence of angioedema, duration of disease and ANA positivity when compared with control (n=24) and uncontrolled (n=83) patients (respectively, p=0.842, p=0.646, p=0.347, p=0.590, p=0.316). Conclusion: In children, atopic diseases, infections, parasitic infestations are present in the etiology of CSF, where as in most cases the diagnosis remains idiopathic.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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