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Amaç: Bu çalışma ile Kırıkkale Üniversitesi Tıp Fakültesi’nde tiroidektomi operasyonu uygulanmış hastalara ilişkin tiroid ince iğne aspirasyon biyopsisi (TİİAB) sonuçları ile histopatoloji rapor sonuçlarının karşılaştırılarak kesitsel bir incelemenin yapılması ve tiroid nodüllerindeki TİİAB etkinliğinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Kırıkkale Üniversitesi Tıp Fakültesi Hastanesi’nde Ocak 2016 - Haziran 2018 tarihleri arasındaki 2.5 yıllık dönemde tiroidektomi uygulanmış 75 hastaya ait TİİAB verileri ve histopatoloji rapor sonuçları çalışmamızın materyalini oluşturdu. TİİAB sonuçları benign, önemi belirsiz atipi veya foliküler lezyon (AUS/FLUS), foliküler neoplazi veya foliküler neoplazi için şüpheli lezyon (FN/SFN), malignite yönünden kuşkulu (SuspM), malign ve tanı için yetersiz (NDS) olarak sınıflandırıldı. Bulgular: Tiroidektomi operasyonu uygulanan vakaların TİİAB sonuçları değerlendirilmiş ve bu vakalardan 26’sına (%34.7) benign, 3’üne (%4) AUS/FLUS, 6’sına (%8) FN/SFN, 18’ine (%24) SuspM, 7’sine (%9.3) malign ve 15’ine (%20) de NDS olarak tanı verildi. Sitoloji sonucu benign olarak değerlendirilen olguların 4’ü, AUS/FLUS olarak değerlendirilen olguların 2’si, SuspM olarak değerlendirilen olguların 15’i ve malign olarak değerlendirilen 7 olgunun ise tamamı doku tanısı bakımından maligndi. Çalışmamızda duyarlılık, özgüllük, pozitif prediktif değer ve negatif prediktif değer sırasıyla %74.2, %91.7, %92 ve %73.3 olarak hesaplandı. Sonuç: Bulgular bir arada değerlendirildiğinde TİİAB tekniğinin tiroid nodüllerine yaklaşımda etkin ve kolay uygulanabilir bir yöntem olduğu sonucuna varılmıştır. Günümüzde TİİAB materyallerinin değerlendirmesinde büyük öneme sahip olduğu ve yaygın olarak kullanılmakta olan, "Tiroid Sitopatoloji Raporlaması için Bethesda Sistemi" ile TİİAB tanılarında standardizasyonunun sağlandığı düşünülmüştür.
Purpose: This study is aimed at conducting a cutting-edge examination by comparing the results of thyroid thin injection aspiration biopsy (TIAB) with the results of the histopathology report and assessing the effectiveness of the TIAB in the thyroid nodes. Tools and Methods: TIIAB data of 75 patients applied thyroidectomy in the 2.5 year period between January 2016 and June 2018 at the University of Kırıkkale Medical School Hospital and histopathology report results formed the material of our study. TIIAB results were classified as benign, uncertain atypical or follicular damage (AUS/FLUS), suspected damage for follicular neoplasm or follicular neoplasm (FN/SFN), suspicious for malignity (SuspM), malign and insufficient for diagnosis (NDS). Results: TIIAB results of cases applied for thyroidectomy surgery were evaluated and 26 of these cases were diagnosed as benign (34.7 percent), 3 percent (4 percent) AUS/FLUS, 6 percent (8 percent) FN/SFN, 18 percent (24 percent) SuspM, 7 percent (9.3 percent) malign and 15 percent (20 percent) NDS. 4 of the phenomena assessed as benign, 2 of the phenomena assessed as AUS/FLUS, 15 of the phenomena assessed as SuspM and 7 of the phenomena assessed as malign were all malign in terms of tissue diagnosis. Our study calculated sensitivity, specificity, positive predictive values and negative predictive values as 74.2, 91.7, 92% and 73.3% respectively. Result: When the findings were evaluated together, it was concluded that the TIIAB technique is an effective and easy-to-apply method in the approach to the thyroid nodes. Today it is believed that it has a great importance in the assessment of TIIAB materials and is widely used, with the "Bethesda System for the Reporting of Thyroid Cytopathology" standardization in TIIAB diagnoses is provided.
Objective: The aim of this study was to compare the results of thyroid fine needle aspiration biopsy (TFNAC) and histopathology report of patients who underwent thyroidectomy operation in Kırıkkale University Faculty of Medicine. Material and Methods: The TFNAC data and histopathology reports of 75 patients who underwent thyroidectomy for 2.5 years between January 2016 and June 2018 in Kırıkkale University Medical Faculty Hospital were the material of our study. The TFNAC results were classified as benign, unclear atypia or follicular lesion (AUS/FLUS), suspicious lesion for follicular neoplasia or follicular neoplasia (FN/SFN), suspicious for malignancy (SuspM), malignant and insufficient for diagnosis (NDS). Results: The TFNAC results of the cases undergoing thyroidectomy were evaluated and of these patients 26 (34.7%) benign, 3 (4%) AUS / FLUS, 6 (8%) FN / SFN, 18 (24%) SuspM, 7 (%9.3) malignant and 15 (20%) NDS cases were determined. When compared with cytological examination results, tissue diagnoses were malignant in 4 of the cases evaluated as benign, 2 of the cases evaluated as AUS/FLUS, 15 of the cases evaluated as SuspM and all of the 7 cases considered malignant. In our study, sensitivity, specificity, positive predictive value and negative predictive value were 74.2%, 91.7%, 92%and 73.3%, respectively. Conclusion: When the findings are evaluated together, it is concluded that the TFNAC technique is effective and easy to apply in the management of thyroid nodules. It has been thought that standardization in the diagnosis of TFNAC with the use of "Bethesda System for Thyroid Cytopathology Reporting" is of great importance in the evaluation of TFNAC materials and is widely used.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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