Özet:

Sjögren’s Syndrome (SS) is a chronic, systemic and autoimmune disease which mainly affects lacrimal and salivary glands via lymphocyte cell infiltration, destruction and dysfunction of the exocrine glands (2). This inflammation is speculated to be caused by B lymphocytes (5). SS is characterised by dry eye (xerophthalmia, keratoconjunctivitis sicca), dry mouth (xerostomia) and hypertrophy of the parotid gland (2). During the course of SS anemia, leucopenia, thrombocytopenia, and lymphoproliferative disorders can occur as extraglandular hematological involvement (6). Here we present a case with isolated thrombocytopenia (33,000 / mm3) dedected on routine tests since the last 3 months and has been referred to us with the suspicion of an underlying rheumatologic diesease. The case was diagnosed as primary Sjögren’s Syndrome and hydroxychloroquine 200 mg 1x1 / day and prednisolone 4 mg 1x1 / day was started. Improvement of platelet count (195,000 / mm3) and decline in joint complaints occured in the first month. Sjögren’s syndrome should be kept in mind as a rare cause of thrombocytopenia and rheumatological evaluation must be included in differential diagnosis.

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