Abstract:

There is increasing evidence in the literature emphasizing the importance of right ventricular(RV) imaging in the prognosis of pulmonary hypertension. We aimed to investigate the predictive role of RV dysfunction parameters assessed by echocardiography(ECHO) and thorax computed tomography(CT) in developing CTEPH. Patients diagnosed with pulmonary embolism(PE) prospectively included. All patients underwent ECHO and CT within 24hours after admission. We repeated CT and ECHO after 6 months and 1 year to assess the incidence of CTEPH and assess the predictive role of RV dysfunction factors in the development of CTEPH. Twenty-two patients (7 of whom were male) with a mean age of 53.9±17.9years were included; CTEPH developed in two patients during the follow-up. Baseline PO2 levels were significantly lower in patients with CTEPH(61.5±11.4vs77.8±25.2,p<0.05). The baseline RV diameter, RV EF, and systolic PAP levels evaluated by ECHO differed significantly in two patients who developed CTEPH. The lowest RVS were detected in two patients that developed CTEPH (-10.3%and-11.7%). This study claimed that the presence of hypoxemia, decreased RV EF, RVS, increased systolic PAP values in ECHO, and increased RV/LV ratio evaluated in thorax CT indicate the severity of RV dysfunction in acute PE and may predict CTEPH development.

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