Özet:

Objective: There is not enough data about how thyroid hormones were affected in geriatric dialysis patients and whether age and duration of disease could be considered as additional risk factors for the thyroid function test abnormalities. For this reason we aimed to compare thyroid function tests of elderly chronic dialysis patients and elderly healthy controls. Methods: Forty six chronic dialysis patients (24 peritoneal dialysis (PD) and 22 hemodialysis(HD)) and 44 healthy controls were taken into the study. After the physical examination, we collected patients’ and controls’ fasting blood samples and thereafter thyroid function tests were performed. In dialysis group thyroid stimulating hormone (TSH), free triiodothyronine (fT3) and free thyroxine (ft4) analysis of all patients were performed, but in control group free hormone levels were not studied at 14 of 44.  Results: Serum TSH and fT4 levels were similar in two groups, however fT3 levels were found to be less in dialysis group ( 2.48 ± 0.57 and 3.06 ± 0.90 p= 0.003). Low fT3 syndrome was not detected in controls, but 7 (15,2%) patients have had  low fT3 syndrome in dialysis patients (p=0,01). The rate of thyroid function test abnormalities were higher at dialysis patients as compared with controls, 22 (47,8%) and 12 (40 %), respectively (p=0,05). Conclusions: Elderly dialysis patients had higher thyroid function test abnormalities than controls. They had lower fT3 levels than controls such as young and middle age chronic dialysis patients. However, what does it mean for clinical process and how its clinical expression is not clearly known, especially in an elderly patients. Large, prospective, randomized and controlled trials are necessary for this topic. Key words: dialysis, elderly, free T3

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