In general, it has a protective effect against the harmful effects of UV rays in the living organism. After the discoveryof ozone in different patients (hepatic steatosis, chronic ulcer, orthopedic diseases, cancer, immunodeficiency,infected wounds, fistula, burn, mastitis, etc.) was used as a therapeutic agent O3 suppresses inflammatory cell factors,activates cyclooxygenase and reduces stress reactions to histiocytic oxidations and increases histiocytic ability toresist oxidation and free radicals. It increases the production of antioxidant enzymes while restoring cell homestasis.It shows free radicals due to chronic inflammation, pain relief and antiinflammatory effect. In the immune system,it acts as an ozone modulator. Different application methods such as medical ozone, intraperitoneal, intramuscular,intraarticular, subcutaneous can be applied and can cause local irrigation. The purpose of this review is to evaluatethe general properties of ozone, the application of medical ozone and its use in veterinary medicine for treatment.
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