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Preeklamptik Kadınlarda Plazma Lipoprotein(A) Düzeylerinin Önemi
2005
Journal:  
Southern Clinics of Istanbul Eurasia
Author:  
Abstract:

AMAÇ: Çalışmamızda Lipoprotein(a) [Lp(a)] düzeylerinde hafif, ağır preeklamptik ve normal gebelikler arasında fark olup olmadığını ve hastalığın şiddeti ile ilişkisini araştırmak istedik. Kliniğimize 01.01.2003 ile 01.04.2004 tarihleri arasında başvuran ve yapılan incelemeler sonucu preeklampsi tanısı alan toplam 26 gebe çalışmaya dahil edildi. Preeklamptik olgulardan 18 gebe hafif preeklamptik (arteriyel kan basıncı sistolik 140-160 mmHg, diyastolik 90-100 mmHg) ve 8 gebe ağır preeklamptik (arteriyel kan basıncı sistolik >160 mmHg, diyastolik >110 mmHg) olarak gruplandırıldı. Kontrol grubu olarak 18 gebe (arteriyel kan basıncı sistolik <140 mmHg, diyastolik <90 mmHg) seçildi. Hafif preeklamptik grup 31-40. gebelik haftaları (ortalama 36.1±4.5 gebelik haftası) arasında, ağır preeklamtik grup 35-38 gebelik haftaları (ortalama 35.2±5.3 gebelik haftası) arasında, normal gebeler ise 36-40. gebelik haftaları (ortalama 38.1±3.2 gebelik haftası) arasındaydı. Tüm gruplardan venöz kan örneklemeleri yapıldı. Spektrofotometrik olarak ölçülen plazma Lp(a) düzeyleri preeklamptik grup ile normal klinik bulgu veren gebeler arasında karşılaştırıldı. Ortalama Lp(a) plazma düzeyleri normal gebelerde 9.3±0.9 mg/dl, hafif preeklamptik gebelerde 18.6±2.3 mg/dl, ağır preeklamptik gebelerde 27.5±2.4 mg/dl ölçüldü (p<0.001). Sonuç olarak normal ve preeklamptik gebelerde plazma Lp(a) düzeyleri arasında anlamlı bir ilişki saptandı. YÖNTEMLER: BULGULAR: SONUÇ:

Keywords:

The importance of plasma lipoprotein(A) levels in preeclamptic women
2005
Author:  
Abstract:

Goal: In our study, we wanted to investigate whether there is a difference between light, severe preeclamptic and normal pregnancies in the levels of Lipoprotein(a) [Lp(a]] and the relationship between the severity of the disease. A total of 26 pregnancies diagnosed with preeclampsia were included in our clinic between 01.01.2003 and 01.04.2004, and the results of the examinations were conducted. 18 pregnancy preeclamptics (arterial blood pressure systolic 140-160 mmHg, diastolic 90-100 mmHg) and 8 pregnancy heavy preeclamptics (arterial blood pressure systolic >160 mmHg, diastolic >110 mmHg) were grouped. The control group was selected for 18 pregnancies (arterial blood pressure systolic <140 mmHg, diastolic <90 mmHg). Light preeclamptic group 31-40 weeks of pregnancy (medium 36.1 ± 4. Between 5 weeks of pregnancy, the heavy preeclamic group was between 35-38 weeks of pregnancy (medium 35.2±5.3 weeks of pregnancy) and normal pregnancy between 36-40 weeks of pregnancy (medium 38.1±3.2 weeks of pregnancy). Venues blood samples were made from all groups. Plasma Lp(a) levels, spectrophotometrically measured, were compared between the preeclamptic group and pregnancies with normal clinical findings. The average Lp(a) plasma levels were measured at 9.3±0.9 mg/dl in normal pregnancies, 18.6±2.3 mg/dl in light preeclamptic pregnancies and 27.5±2.4 mg/dl in heavy preeclamptic pregnancies (p<0.001). As a result, a meaningful relationship between plasma Lp(a) levels was found in normal and preeclamptic pregnancies. Methods: Bulgarians: Results:

Keywords:

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Southern Clinics of Istanbul Eurasia

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

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Southern Clinics of Istanbul Eurasia