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6
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11
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2
Toll like receptors are the innate immune receptors, responsible for the identification of pathogens. Ten different toll like receptors have been described in humans. Toll-like receptors are being activated by both exogenous ligands (bacterial, viral ve fungal pathogens) and endogenous ligands released from damaged cells. The several of studies show that toll like receptors signaling is important in the pathogenesis of disease as cancer, diabetes mellitus, atherosclerosis, renal disease, gastrointestinal disease, lung disease, central nervous system disease, autoimmune disease. The aim of this review is to define the role of toll like receptors in the pathogenesis of various diseases.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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