Özet:

In the world, breast cancer is the highest in women's cancer deaths. Methods such as chemotherapy, radiotherapy, hormonal therapy, although used for the treatment of breast cancer, metastases and nurses are frequently encountered. The most impressive factor in the failure to effectively provide breast cancer treatment is the cancer root cells that make up a small population in the tumor tissue. Studies on the elimination of breast cancer root cells include approaches that can be effective on developmental signal pathways that play a critical role in the appearance of root cells properties. Notch signal pathway, one of the most important pathways of developmental signals, is very effective on apoptosis, proliferation, angiogenesis and differentiation mechanisms in breast cancer root cells. Current studies show that Notch signal pathway, which plays a critical role in the characteristics of cancer root cells, is important for effective treatment approaches of inhibition. This collection will discuss the different approaches introduced to the inhibition of the Notch signal path in the treatment of breast cancer and discuss the methods that may be useful in the development of effective cancer treatment in the future.

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