Özet:

Objective: In our study we aimed to evaluate the findings of female patients presenting with a complaint of the onset of puberty according to the etiological factors and to discuss the findings in the literature. Material and Methods: Ninety-six girls presenting to the pediatric endocrinology clinic patients were enrolled in the study. Anthropometric measurements and pubertal status of the patients were evaluated. In the evaluation of patients with suspected early puberty, follicle stimulating hormone (FSH), Luteinising Hormone (LH), estradiol (E2), dehydroxyepiandrostenedione sulfate (DHEA-SO4), 17-hydroxyprogesterone (17OHP) levels, and luteinizing hormone releasing hormone (LHRH) stimulation test results were used. The bone age and pelvic ultrasound results were recorded. Results: The mean age of the patients was 8.38 ± 1.72 years. We found premature thelarche in 14.6% of the patients (n = 14), premature pubarche in 4.2% (n = 4), premature menarche in 3.1% (n = 3), and precocious puberty in 8.3% (n = 8) while 21.9% (n = 21) were normal variants of pubertal development. 46.9% of admitted patients (n = 45) had normal pubertal development, 22.9% (n = 22) had an acceleration in pubertal development over eight years. 21.9% (n = 21) of patients had atypic pubertal development. Conclusion: The decrease in the age of the onset of puberty has increased applications to the endocrine clinic. Most of the applications are normal variants of puberty. We wanted to highlight the good diagnostic evaluation of these patients in this study.

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