Özet:

Objective: To determine the value of fine needle aspiration biopsy (FNAB) and ultrasound findings for differentiating benign and malignant thyroid nodules in patients who underwent thyroidectomy in our clinic. Material and Methods: In this retrospective study, the charts of 290 patients who underwent total thyroidectomy or isthmolobectomy in Otorhinolaryngology and Head and Neck Surgery Clinic of our hospital between 2009 and 2013 were analyzed retrospectively. The demographic characteristics, preoperative ultrasonographic findings, FNAB biopsy and histopathological findings of the patients were analyzed. FNAB results were classified according to the Bethesda thyroid cytopathology system, published in 2009. Results: Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy rate of ultrasonography in predicting malignant and benign nodular thyroid disease were 69.1%, 64.6%, 43.1%, 84.4%,and 65.9%, respectively. Sensitivity, specificity, PPV, NPV and accuracy rate of FNAB were 39.5%, 94.7%, 74.4%, 80.2%, and 79.3%, respectively. The postoperative diagnosis was malignant in 27% of the patients who were diagnosed with follicular neoplasm or suspicion of follicular neoplasm by FNAB, 60% in the ones diagnosed with suspected malignancy, and 94.4% in the ones diagnosed with malignancy. Conclusion: Thyroid ultrasound is highly sensitive and specific in the diagnosis of nodular thyroid disease. The rate of postoperative malignant diagnosis in patients diagnosed with follicular neoplasm or suspicion of follicular neoplasm, suspected malignancy, and malignancy by FNAB were consistent with the literature. However, the patients diagnosed with benign cytology, atypia of undetermined significance, and follicular lesion by FNAB had higher risks for malignancy when compared with the literature.

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