Özet:

Stenotrophomonas is a type of bacterium that is found in the maltophilia gamma proteobacteria and is often isolated from both humans and animals. One of the most notable features of S. maltophilia is the high antibiotic resistance that the bacteria develops in various forms, including intrinsic mechanisms. This study was aimed at measuring the interaction of S. maltophilia, which was isolated from horses, with timokionone and the combination of various antibiotics. No interaction was measured in the form of synergism or antogonism. However, the antibacterial effect of timokionone on S. maltophilia juices was detected.

Anahtar Kelimeler:

Özet:

Stenotrophomonas maltophilia is a member of gamma proteobacteria that has been frequently isolated from humans as well as from animals. One of the most outstanding feature of S. maltophilia is its antibacterial resistance that is basicly controlled by various pathways including intrinsic manner. By this study we aimed to evaluate the interaction of S. maltophilia suspected equine strains with various antibiotics in the presence of Thymoquinone in vitro. Disc diffusion technique was used for measuring interactions between the thymoquinone and others. No measurable inhibition zone for synergistic or antagonistic effect between the thymoquinone and test antibiotics was observed. However, the thymoquinone itself has an antibacterial potential.