Özet:

Introduction and Purpose: Resistant is a cytokine associated with insulin resistance, inflammation and immunity. The relationship of resistance with the tumor necrosis factor (TNF)-α, which is one of the main cytokines of periodontal inflammation, is double. This study aims to assess the levels of sperm resistance and TNF-α in different periodontal diseases. Method and Requirements: Examples of scratch were obtained from 20 common aggressive periodontitis (Y-AgP), 20 chronic periodontitis (KP), 20 patients with gingivitis and 20 periodontal healthy individuals. Filed cell depth (SCD), clinical attachment level (CAS), papillular bleeding index (PCI) and plaque index values were recorded. The levels of scratch resistin and TNF-α were analyzed by the enzyme-related immunosorbent method. Intergroup comparisons were made with the Kruskal-Wallis test and the Dunn post-hoc test. The levels of sperm resistance and TNF-α of the Y-AgP, KP and gingivitis groups were higher than periodontal healthy individuals but this difference was not statistically meaningful (p>0.05). Although the average values of both periodontitis groups were SCD, CAS and PCI significantly higher than the gingivitis group (p<0.0001), the levels of cytokines in sputum were similar between groups (p>0.05). IN THE LIMITES OF THIS STUDY, the levels of sperm resistance and TNF-α have not been separated from periodontal disease, periodontal health. Advanced studies with a wider sample size are needed to illuminate the possible relationship between the levels of these cytokines in the sputum and periodontal inflammation.

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