Abstract:

Purpose: There is no accurate information about the antibodies produced in response to the coronavirus disease 2019 (COVID-19) infection. Knowing the levels of antibodies in different patients groups is life. Our study aimed at comparing the levels of immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies developed against COVID-19 infection according to age groups and initial complaints. The drug and method: IgM and IgG levels in serum samples were studied on the day of diagnosis and on the 21st day in four COVID-19 patients. The antibodies were evaluated according to age groups and clinical complaints. Results: The first day IgM levels increased significantly from the 21st day and the 21st day IgG levels increased significantly from the first day (respectively, p=0.006, p<0.001). The first day is IgG and 21. The day IgM levels were positive (>1). The IgG-type antibodies are overwhelming in children, while strong antibodies are observed in adults over 65 and younger. Result: The severe acute respiratory syndrome coronavirus-2 IgM antibodies, which are formed against coronavirus protein, appear to be original to Sars-Cov-2, despite the formation of IgG antibodies from the first day, they do not provide a complete protection against infection. IgG-type antibodies are overwhelming in childhood, while strong IgG and IgM-type responses can be detected in young adults and older people. According to clinical findings, different antibodies can develop.

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