Özet:

Autoimmune hepatitis (OIH) is a chronic, necroinflammatory liver parenchymal disease that occurs in the absence of an etiologic agent known to cause chronic hepatitis in the liver. OIH presents with various clinical variants. Some patients with cholestatic liver disease (such as primary biliary cholangitis [PBC] and primary sclerosing cholangitis [PSC]) have clinical and serological features that indicate the presence of autoimmune hepatitis and may respond to immunosuppressive therapy. However, sometimes the diagnosis cannot be clarified in patients and it may be necessary to go from treatment to diagnosis. In this article, we presented a 33-year-old autoimmune hepatitis-cholangitis case, who was admitted with elevated aminotransferase and bilirubin levels, pruritus and icterus, the diagnosis of AIH could not be clarified after evaluation and was thought to be toxic hepatitis at first, but diagnosed after treatment. In conclusion, autoimmune hepatitis-cholangitis should be kept in mind in the differential diagnosis of all cases with elevated liver enzymes.

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