Abstract:

Objective: In adult patients with chronic period of medium or severe traumatic brain damage (TBH), the aim is to compare the levels of the pre-hypofysic hormone, functional, cognitive and emotional results, to determine the relationship of these parameters with the severity of trauma. Tools and Methods: The study included 53 patients with TBH for at least 6 months. The severity of the trauma was determined by the Glaskow Koma Scale (GKS) score recorded in the first 24 hours, the patients were divided into 2 groups as medium (n=20) and heavy TBH (n=33) . The Functional Independence Scale (FBÖ), Mini Mental Status Test (MMDT), Ranchos Los Amigos Cognitive Function Scale (RLAS), Beck Depression Scale (BDÖ) and Beck Anxiety Scale (BAÖ) were used for assessments. Additionally, the adrenocorticotropic hormone, prolactin, follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, insulin-like growth factor-1 and growth hormone basal levels were measured in all patients. Results: Between patients with medium and severe TBH there were significant differences in terms of the values of FBÖ, MMDT, BDÖ and BAÖ but the basal levels of the front hypofysic hormone did not differ. The positive relationship between GKS and FBÖ and MMDT, the negative relationship between BDÖ and BAÖ, while the relationship with the front hypofysic hormone levels was not found. The result: As the severity of the trauma increases in patients with chronic TBH, addiction, depressive emotions, anxiety and disruption in cognitive functions increases in their daily life activities. Therefore, the recording of the GKS score is valuable in the subsequent rehabilitation process, especially in terms of determination of clinical results.

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