Henoch-Schönlein purpura is characterized histopathologically by small vessel vasculitis with immunoglobulin A-dominant immune complex deposition. Purpuric skin rash, glomerulonephritis, and gastrointestinal tract involvement are typical clinical findings of the disease. The majority of patients are under 20 years of age. It is seen more rarely in adults, and the clinical presentation is somewhat different from that in children. Gastrointestinal symptoms are less frequent in children than in adults. Another feature of the disease, familial Mediterranean fever, is observed with significantly higher frequency in children (130/1000). Nevertheless, Henoch-Schönlein purpura and seronegative spondyloarthropathy has been reported as a rare combination. We report herein a case presenting with gastrointestinal bleeding and purpuric skin rash, in whom, interestingly, ankylosing spondylitis was also detected
Henoch-Schönlein purpura is characterized histopathologically by small vessel vasculitis with immunoglobulin A-dominant immune complex deposition. Purpuric skin rash, glomerulonephritis, and gastrointestinal tract involvement are typical clinical findings of the disease. The majority of patients are under the age of 20. It is seen more rarely in adults, and the clinical presentation is somewhat different from that in children. Gastrointestinal symptoms are less frequent in children than in adults. Another feature of the disease, family Mediterranean fever, is observed with significantly higher frequency in children (130/1000). Nevertheless, Henoch-Schönlein purpura and seronegative spondyloarthropathy has been
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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