Özet:

In this study the effect of carprofen treatment on conception rate after insemination in Holstein cows that did not conceive for a long time after parturition was evaluated. In the study, 200 Holstein cows with days in milk >120 were used. A progesterone + ovsynch-based estrus synchronization protocol was applied to the cows included in the study. For this purpose, the progesterone device was placed intravaginally together with GnRH injection. Seven days later, the progesterone source was removed from the vagina and PGF2α injection was administered. GnRH injection was administered 48 hours following PGF2α injection and fixed-time insemination was performed 12-16 hours later. After insemination, animals were randomly divided into 2 groups. Subcutaneous carprofen was applied to the carprofen group (n = 100) on the 14th day after insemination and physiological saline was applied to the control group (n = 100) on the same day. Three cows from the carprofen group and 5 cows from the control group were excluded from the study for various reasons. The pregnancy rate was 42.26% (41/97) in the carprofen group and 25.26% (24/95) in the control group (p <0.05). However, the rate of conception was found to be the lowest (10.52%) in cows with high milk yield (>30 kg) in the control group. In addition, it was found that carprofen administration to cows with high milk yield increased the rate of conception. However, it was determined that the days in milk had no effect on pregnancy rate. As a result, it was concluded that the administration of carprofen on the 14th day after insemination to cows who could not conceive for a long time after parturition may be effective in increasing the rate of conception.

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