Özet:

Objective: Arterial stiffness reflects the viscoelastic properties of the vessel wall. In this study, we aimed to evaluate the relationship between aortic strain, elasticity, stiffness, and left ventricle functions in obese and obesity-prone young adults. Materials and Methods: The participants were classified as obese, overweight, normal-weight, and underweight, according to the BMI. There were 28 underweight, 84 normal weight, 89 overweight, and 22 obese individuals. Physical examinations, findings and medical history of patients were recorded. Left and right ventricle functions were evaluated with 2D transthoracic echocardiography. Parameters of aortic elasticity including aortic strain, elasticity, and stiffness index were calculated according to the predefined formula. Results: Baseline clinical and demographic findings were similar, except age and weight. In the comparison of echocardiographic measurements, left ventricular end-systolic and end-diastolic diameters, interventricular septum and posterior wall diastolic diameters, left atrial diameter, left ventricular mass and mass index were significantly higher between groups as consistent with the increase in BMI, mitral early diastolic filling velocities, mitral early and late diastolic filling velocity ratio and mitral lateral early diastolic relaxation were significantly lower between groups as conversely with the increase in BMI (p < 0.05, for all). Statistically significant differences were observed between groups regarding aortic strain, elasticity, and stiffness values. Aortic strain were significantly higher between groups as consistent with the increase in BMI, aortic strain and elasticity were significantly lower between groups as conversely with the increase in BMI (p < 0.05, for all). BMI, systolic blood pressure, pulse pressure, and myocardial performance index (MPI) were found as independent variables affecting the aortic stiffness index (β). Conclusion: Aortic stiffness index (β), which might have a prognostic value in determining the risk of future CV disease, tends to be increased in obese and obesity-prone young adults, and correlated with the increase in BMI, systolic blood pressure, and left ventricle MPI.

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