Özet:

To evaluate changes in platelet index in preterm labor and to investigate whether there is a predictive value for preterm labor. Retrospectively, women with 140 preterm labor and 130 healthy pregnant women between 2013 and 2016 were included in the study. Demographic, obstetric and laboratory results (hemoglobin, hematocrit, white blood cell, platelet, platelet distribution width, mean platelet volume) of 270 pregnancies were compared. Mean platelet volume (MPV) and hemoglobin levels were significantly lower in the preterm labor group (p <0.001, p = 0.01, respectively). Platelet distribution width (PDW) levels were higher in the preterm labor group (p = 0.05). There was no significant difference between platelet counts in both groups. Successful coagulation and anticoagulation stabilization are very important for the formation and progression of the pregrancy. For this, many markers such as PDW, MPV have been studied. More recently, however, blood subtypes are thought to be able to provide clues for prognosis and diagnosis in chronic low-grade inflammation-related diseases. MPV levels in preterm labor suggest that high levels of low PDW levels may be due to pathologic thrombocyte activation and inflammation. Further PDW levels may alert the obstetrician to the risk of preterm labor. However, there is a need for further study for the beneficial role of platelets in the diagnosis of preterm labor.

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