Abstract:

The purpose: Families who do not have a baby with natural reproductive methods apply to assistant reproductive techniques (IVF). This study examined the differences between the two groups of infants born with IVF and infants born as a result of spontaneous pregnancy in terms of cardiovascular function and anomaly. The study has been followed by the Department of Child Cardiology Sciences of the University of Horizon, with a total of 127 facts, including 50 facts born with IVF and 77 facts born with spontaneous pregnancy. With ecocardiography, all the facts were assessed in terms of congenital anomaly and left ventricular functions. The left ventricular wall thickness, ventricular diameter, injection and cutting fractions were calculated. Results: In 127 patients involved; the average age of IVF babies was 14.46±14.8 months; the average age of spontanely born babies was 4.42±5.7 months. 25 of IVF babies were girls (50%), 25 men (50%); 36 of babies born with spontaneous pregnancy were girls (46.7%), 41 men (53.3%). In the study, 18 of those born with spontaneous pregnancy (23%) and 10 of those born with IVF (25%) found heart abnormalities. When the left ventricular wall thickness was assessed, there was no difference between the occurrences of spontaneous pregnancy and the occurrences of IVF (p>0,05). In cases born with IVF of the left ventricular sistol end diameter, EF and FS values were statistically significantly high in all age groups in cases born with spontaneous pregnancy (p<0,05). Result: In recent years, there are publications that support that the prevelancy of parental anomaly in infants born with IVF is similar to the infants born as a result of spontaneous pregnancy. In our study, these data are supported in terms of maternal cardiovascular anomaly. However, left-heart functions have been detected lower in babies born with assistant reproductive techniques, it has shown that these babies should be monitored for a longer period of time at certain intervals. The aim of this study was to investigate the differences of cardiac function and anomaly between babies born with ART and babies born as a result of spontaneous pregnancy. Material and Method: A total of 127 cases examined in the University Department of Pediatric Cardiology, including 50 cases born with ART and 77 cases born with spontaneous pregnancy, were included in the study.All patients were evaluated for congenital anomaly and left ventricular function by echocardiography.Left ventricular wall thickness, ventricular diameter, ejection and shortening fractions were calculated. Results: 127 patients included in the study; The average age of ART babies was 14.46 ± 14.8 months; The average age of the babies born with spontaneous pregnancy was 4.42 ± 5.7 months. 25 were female (50%) and 25 were male (50%) in ART group; 36 were female (46.7%) and 41 were male (53.3%) in spontaneous pregnancy group. 18 (23%) cardiac anomalieswere detected in spontaneous pregnancy group and 10 (25%) cardiac anomalieswere detectedin ART group. When the left ventricular wall thicknesses were evaluated, no difference was found between the cases born with spontaneous pregnancy and ART (p> 0.05). In all age groups, left ventricular end-systolic diameter was found to be significantly higher in ART group, EF and FS values were found to be significantly higher in spontaneous pregnancy group (p <0.05). Conclusion: Recent studies suggest that the prevalence of congenital anomaly in infants born with ART is similar to those born with spontaneous pregnancy.Our study supports these data about congenital cardiac anomaly. However, although left heart functions were found to be lower in babies born with ART, it was shown that these babies should be monitored for longer periods at regular intervals.

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