Özet:

Propolis is a resin like natural material that bees collect from various parts of plants. Bees use propolis as protective against various pathogens. Propolis has many biological effects due to its rich content. Perga is a fermented product of pollen and honey that bees use to feed their offspring. The aim of this study is to compare the perga, which is rich by phenolic compounds, to the propolis for its antimicrobial activity.Ethanolic extracts of the propolis and perga were prepared and total phenolic compound quantity determination were made according to the Folin-Ciocalteu method. The minimum inhibitory concentration (MIC) values of the extracts on Escherichia coli and Pseudomonas aeruginosa which are gram-negative pathogens, Staphylococcus aureus which is a gram-positive pathogen, and Candida albicans which is a fungus were measured by microdilution method. The MIC test range for propolis and perga was determined as 0.06µg/mL-125µg/mL, depending on the amount of phenolic compounds.Propolis showed an inhibitory effect at low concentrations against Candida albicans and Staphylococcus aureus compared to Escherichia coli and Pseudomonas aeruginosa. It has been determined that perga has an inhibitory effect at low concentrations against Escherichia coli, Pseudomonas aeruginosa and Candida albicans; although, it was determined that more higher concentrations are required for perga to show inhibitory activity against Staphylococcus aureus.As a result, it was observed that propolis and perga exhibited antimicrobial effects in our study.

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