Özet:

Background: Primary hyperparathyroidism is an endocrine hormone disorder disease characterized by hypercalcemia with excessive secretion of parathyroid hormone from the parathyroid glands. The most common cause is parathyroid adenomas. Curative treatment is the surgery. In this study, we aimed to present the results of 47 patients operated for primary hyperparathyroidism Material and Methods: Data of 47 patients who have been treated surgically with diagnosis of parathyroid adenoma between 2009 and 2017 were analyzed retrospectively. Results: Forty 0ne patients were female, 6 were male and the mean age was 52.53 (range 21-76 years). The most common symptom patients was bone and joint pain with 21 patients. Preoperative mean PTH values were 381.8 (116-1348) pg / mL, mean Ca values 11.1 (9.7-14.2) mg / dL. The accuracy rate for pathologic parathyroid gland localization study was 75 % in neck USG, 85 % in parathyroid scintigraphy, and 40 % in neck CT. The mean PTH values measured at postoperative 12th hour were 84.1 (4-808.2) pg / ml and mean Ca values were 9.1 (6.7-12.35) mg / dl, whereas 36th hour were 83, 27 (4-435) pg / ml, Ca values 8.8 (7.3-12.19) mg / dl. Parathyroid the PTH values at postoperative Histopathology was parathyroid adenoma in 45 patients and parathyroid hyperplasia was in 2 patients. Thyroid surgery was performed in 18 patients because of accompanying thyroid disease Simultaneous. When thyroid histopathology was evaluated, 14 patients had adenomatous nodular goiter, 3 patients had thyroid papillary carcinoma, and 1 patient had thyroid medullary carcinoma. Complications were hypocalcemia in 3 patients. Conclusion: Patients with symptomatic PHPT should be treated surgically in order to avoid long-term complications. Risky patients who are thought to develop complications in the future should be operated. In asymptomatic hyperparathyroidism patients. We recommended that parathyroid scintigraphy and neck ultrasonography are used together for preoperative localization. We evaluated that minimally invasive surgery is useful with a successful localization study.

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