Abstract:

Purpose: In our study, we aimed at assessing the relationship between the 25-hydroxyvitamin D [25(OH)D] levels at the time of application of our children with type 1 diabetes and adolescents with clinical, laboratory and tracking data. Methods: The study included the tracking data of existing patients diagnosed with type 1 diabetes mellitus between 2009 and 2015 in our clinic. We scanned patient files for application, resume/family history and results related to clinical, laboratory and tracking data. Additionally, all data were assessed in the context of 25(OH)D scale values for adequacy/deficiency/deficiency. The average age was 8.62 ± 14,19 years. In 53.9% of patients, type 1 diabetes mellitus was diagnosed with diabetic ketoacidosis. The average 25(OH)D level at the moment of diagnosis was 18.90±11.07 ng/mL. In the group with vitamin D deficiency, the average time of ketosis/diabetic ketoacidose resolution to subcutaneous insulin treatment was significantly longer (p=0,020). Patients diagnosed with moderate and severe diabetic ketoacidosis had an average of 25(OH)D levels lower (p=0,020). In addition, insulin doses were significantly lower (p=0,039) in patients with an average level of 25(OH)D of 10-20 ng/mL during the release. During the follow-up period there was no meaningful relationship between vitamin D groups and HbA1c and insulin doses. Result: This study is a pilot study that, in addition to clinical, laboratory and tracking data, assesses the state of honeymoon especially in the 2nd month (±1) . In our study, we found that the level 25(OH)D immediately affects the clinical characteristics of the diagnosis, but does not affect it during the follow-up.

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