Özet:

The coronavirus disease (Covid-19) has become a pandemic since its appearance in December 2019. Covid-19 infection can trigger lung inflammation and also cause acute lungs damage. In cases of severe pneumonia, long stay in the hospital and high mortality rates have been detected. Therefore, there is a need for the presence of biobelirects so that cases can be diagnosed quickly and early. In our study, we aimed at evaluating the laboratory parameters and radiological findings used in Covid-19 patients with ROC curve analysis. Tools and Methods: Our study was planned backward in adult patients diagnosed with Covid-19 in our hospital between May 2020 and July 2020. The data was obtained by scanning the results of patients' routine biochemical and hematological laboratory tests. Laboratory data and radiological findings, receiver work characteristics were compared using ROC curve and Cox regression analysis. Results: A thousand facts (54% men) were studied with an average age of 47.3 ± 17.65 (December: 19-78) years. The RT-PCR result for Covid-19 was positive in all cases. In patients with advanced pulmonary constipation, urine (p < 0.0001), glomerular filtration rate (p < 0.0001), lactate dehydrogenase (LDH) (p < 0.0001), aspartate aminotransferase (AST) (p < 0.0001), neutrophil-lenfocyte rate (p < 0.0001), thrombocyte-lenfocyte rate and C-reactive protein (CRP) (p < 0.0001) were significantly detected. Also, patients with advanced lung constipation had lower levels of hemoglobin (Hb) (p < 0,0001), white cells (WBC) (p < 0,0001), serum albumin (Alb) (p < 0,0001) and lymphocytes (p < 0,0001) compared to others. WBC and CRP were found meaningful in the multi-variable models, respectively p = 0,002 and p < 0,0001. Alb (AUC = 0.77), D-dimer (AUC = 0.68), LDH (AUC = 0.69) and CRP (AUC = 0.77) had a very good accuracy in predicting cases of advanced lung constipation for Covid-19. Result: In order to diagnose Covid patients, indicators are needed to classify patients and identify the progression of the disease. Our findings show that Alb, D-dimer, LDH, and CRP levels can be used specifically to estimate the severity of lung retention in Covid-19 patients.