Abstract:

Objective: It is previously emphasized that the average platelet volume (MPV) is a useful parameter in predicting coronary artery disease and related morbidity and mortality. The purpose of this study is to investigate the relationship between myocardial perfusion scintigraphic findings and average platelet volume (MPV), which is a simple and reliable parameter of platelet function in patients with suspected coronary heart disease. Methods: In this retrospective study, 344 patients who underwent myocardial perfusion scintigraphy in our clinic between 2009 and 2012 were included. The study group consisted of 139 men and 205 women (mean age 56.67±11,16). Based on the scintigraphic findings, patients were divided into three groups as normal, suspicious for ischemia and significant ischemia. The results of MPV and the parameters obtained from GATED myocardial perfusion SPECT scintigraphy such as stress ejection fraction, end-systolic volumes and enddiastolic volumes were correlated. Results: 96 (27.9%) of the patients were normal, 98 (28,5%) were suspicious for ischemia and 150 (43.6%) showed significant ischemia. MPV values of patients were found to be 8.43±1.19 in normal group, 8.10±1.34 in suspicious ischemic group, 8.06±1.23 in significant ischemic group. There was no significant difference between scintigraphic findings and MPV results. (p=0,060) Conclusion: In our study, it was found that there was no relationship between MPV, which is considered as a risk factor for cardiovascular disease, parameters of GATED myocardial perfusion SPECT scintigraphy and myocardial ischemia

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