Özet:

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, which is experienced once in a century and whose end is unpredictable, continues unabated around the world. Despite promising vaccine and drug studies, since the pandemic cannot be controlled, immune plasma continues to be up-to-date as one of the alternative treatment options in the treatment of coronavirus disease 2019 (COVID-19). The use of healed patient plasma in epidemic diseases is not a new method but has been used in the treatment of many infectious diseases in history. The known mechanism of action of neutralizing antibodies (Nab) in the immune plasma is to prevent the entry, fusion, and exit of the virus into the cell. Studies are showing that the use of plasma therapy in the early period (<7 days) decreases the severity of the disease and reduces the length of hospital stay and increases survival. Data accumulated about security It is that immune plasma treatment has similar side effects with other plasma products. It is thought that immune plasma can be an effective and rapid treatment strategy that can directly target SARS-CoV-2 in susceptible individuals. In this review, in light of current data, plasma therapy applications that are rapidly used in the COVID-19 pandemic will be discussed.

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