Objectives: Data on the co-occurrence of stroke and coronavirus disease 2019 (COVID-19) infection are limited and need to be improved. In our study, we aimed to evaluate the clinical and laboratory characteristics of COVID-19-related patients admitted to our center with acute stroke and compare them with acute stroke patients without COVID-19 infection during the same period. Methods: One hundred and eighty-four patients admitted with acute stroke from March 11, 2020, to May 11, 2020, were included in the study. Demographic and clinical characteristics, work-up studies, and clinical scales including National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS) scores were examined retrospectively. All patients diagnosed with acute stroke who were also evaluated for COVID-19 before hospitalization were divided into two groups: COVID-19-related and unrelated cases. Results: COVID-19-related and unrelated acute stroke patients had similar characteristics in terms of age, gender, and stroke risk factors. The admission NIHSS (mean NIHSS: 9.8 vs. 5.9) scores and the discharge mRS values (mean mRS: 3.9 vs. 2.4) were significantly higher in the COVID-19-related stroke group (p=0.002 and p=0.001, respectively). The prognosis of the COVID-19-related stroke group was significantly worse (69.6% vs. 39.8%) and the mortality rate (39.1% vs. 6.2%) was significantly higher than the COVID-19-unrelated stroke group (p=0.007 vs. p=0.000, respectively). The proportion of patients with large infarcts in the COVID-19-related acute ischemic stroke group was significantly higher than the one in the COVID-19-unrelated acute ischemic stroke group (57.9% vs. 21.9%, p=0.003). Conclusion: This is the first comparative study to evaluate the clinical presentation and outcome of COVID-19-related acute ischemic and hemorrhagic stroke patients in Turkey. Our results suggest that COVID-19-related acute stroke is associated with more severe clinical presentation and worse outcome. This seems to be linked to the coagulation abnormalities induced by COVID-19 infection.
Purpose: There is a limited number of data on the conjunction of Inma and Coronavirus Disease 2019 (COVID-19) infection. Our study aims to evaluate the clinical and laboratory characteristics of COVID-19-related patients with acute infection and to compare with acute infection patients without COVID-19 infection during the same period. Tools and Methods: 184 patients with acute infestation from 11 March 2020 to 11 May 2020 were included in the study in our center. The demographic and clinical characteristics of the incidents, diagnosis and etiology examinations and the NIHSS (National Institutes of Health Stroke Scale), mRS (modified Rankin scale) scores were examined retrospectively. All patients diagnosed with acute infestation, assessed for COVID-19 prior to bed, were divided into two groups, COVID-19-related and non-related events. Results: COVID-19-related and non-related patients had similar characteristics compared to age, gender and stroke risk factors. In the COVID-19-related acute infestation group, the input NIHSS and output mRS scores were significantly higher than the COVID-19-related infestation group (respectively 9.8 vs. 5.9; p=0,002 and 3.9 vs. 2.4; p=0,001). The forecast for the COVID-19-related infestation group was significantly worse than the COVID-19-related infestation group, and the mortality rate was significantly higher (respectively 69.6 percent vs. 39.8 percent; p=0,007 percent and 39.1 percent vs. 6.2 percent; p=0,000 percent). The rate of patients with large infarction in the COVID-19-related acute ischemic infarction group was significantly higher than the COVID-19-related acute ischemic infarction group (57.9% vs. 21.9% p=0,003). Result: Our study is the first study in Turkey to evaluate the clinical presence and results of acute ischemic and hemorrhagic stroke patients associated with COVID-19. Our findings suggest that COVID-19-related acute decay is associated with a heavier clinical presentation and a worse end. This situation appears to be associated with increased coagulation abnormalities caused by COVID-19 infection. (SETB-2021-05-127)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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