Özet:

The aim was to evaluate the occurrences of toxic keratopathy and treatment approaches that develop due to the overdose use of topical anesthetics. Methods: In developing keratopathy occurrences due to overdose of local anesthetics applied to our clinic between March 2007 and October 2009, pre- and post-treatment vision accuracy, clinical findings and treatment approaches were reviewed backward. 12 patients with an average age of 39.08±10.02 (distribution of 23-58 years) were 15 observations. The common stories of patients were that they were using local anesthetic drugs chronically with the favorite sense of foreign body and the cause of ocular pain after work with the injury or source with a foreign body. While most patients had epithelial defect in the central cornea in their first application and round stromal infiltration around them, some had hypopion. Seven favourites (47%) only healed epithelial defect with medical treatment, while 8 favourites (53%) did not respond to medical treatment amniotic membrane transplantation (AMT). Despite medical treatment and AMT treatment, the cause of developing desmotosal and spontaneous corneal perforation should be 2 patients with penetrating keratoplasty (PK). Patients with the follow-up periods were on average 12.1±9.2 months with the best corrected vision accuracy before treatment varied between 0.2 and hand movement, while the best corrected vision accuracy after treatment was found at 9 preferences (60%) 0.5 and better, 2 preferences (13) between 0.1 and 0.4 and 4 preferences (27) at 0.05 and less. The toxic keratopathy, which develops due to the overdose use of topical anesthetic medications, may in some cases lead to noticeable vision loss and serious ocular complications. Although successful results can be achieved by medical treatment and surgical initiatives, it is easier to prevent the disease and inform patients about these anesthetic drugs than treatment.

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