Özet:

With its prevalence increasing in recent years, obesity has become a major problem for both developed and developing countries. The energy imbalance associated with increased consumption of high energy diets and reduced levels of physical activity are the main causes of obesity. In recent years, biochemical pathways related to the development of obesity have begun to be investigated. Findings from studies have shown that intestinal microbiota has effects on energy metabolism and plays a role in the pathogenesis of obesity. Intestinal microbiota has functions in the metabolism of polysaccharides and oligosaccharides and in the production of short chain fatty acids. Glucose and lipid metabolism are primarily affected when the microbial diversity decreases with changes in the intestinal microbiota. Changes in glucose and lipid metabolism cause an inflammation in the body, leading to the pathophysiological process of obesity. Microbiota is known to have effects on the human body. However, recent studies show that intestinal microbial activity has a greater effect on metabolism than is predicted. In future studies, intestinal microbiota may play a potential role in the treatment of obesity

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