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 Görüntüleme 7
 İndirme 2
Preeklamptik Gebelerde Trombosit Fonksiyonlarının Agregometre ile Değerlendirilmesi
2013
Dergi:  
Zeynep Kamil Tıp Bülteni
Yazar:  
Özet:

INTRODUCTION: Platelets are thought to be involved in the pathogenesis of preeclampsia. Our objective was to determine the platelet aggregation in preeclamptic patients by aggregometry in the third trimester. METHODS: Normotensive (Group 1, n=10) and preeclamptic patients (Group 2, n=10) were included into the study. All patients were evaluated in outpatient clinic and both clinical and laboratory parameters were recorded prospectively. Platelet aggregation was induced by the RESULTS: In our study, mean age was 27.6±4.3 and 26.7±2.2 years in preeclamptic and normotensive pregnants respectively. The rates of intrauterine growth retardation (IUGR) and preterm delivery were significantly higher in the preeclamptics with respect to the controls (p<0.05). Platelet aggregation was statistically significant in preeclamptic patients compared to the normotensive controls (%43 vs %67, respectively) (p<0.05). There was no difference with regard to the platelet aggregation between severe and mild preeclamptics. DISCUSSION AND CONCLUSION: Our study demonstrated a reduction in platelet aggregation in preeclamptic patients in third trimester. We thought that the observed reduction in platelet aggregation in preeclamptic petients might be related to the endothelial cell dysfunction seen in preeclampsia.

Anahtar Kelimeler:

Assessment of thrombocytes in preeclamptic pregnancies by agregometer
2013
Yazar:  
Özet:

PLATELETS are thought to be involved in the pathogenesis of preeclampsia. Our objective was to determine the platelet aggregation in preeclamptic patients by aggregometry in the third trimester. Methods: Normotensive (Group 1, n=10) and preeclamptic patients (Group 2, n=10) were included in the study. All patients were evaluated in outpatient clinic and both clinical and laboratory parameters were recorded prospectively. Platelet aggregation was induced by the RESULTS: In our study, average age was 27.6±4.3 and 26.7±2.2 years in preeclamptic and normotensive pregnancies respectively. The rates of intrauterine growth retardation (IUGR) and early delivery were significantly higher in the preeclamptics with respect to the controls (p<0.05). Platelet aggregation was statistically significant in preeclamptic patients compared to the normotensive controls (43% vs 67, respectively) (p<0.05). There was no difference with regard to the platelet aggregation between severe and mild preeclamptics. DISCUSSION AND CONCLUSION: Our study demonstrated a reduction in platelet aggregation in preeclamptic patients in the third trimester. We thought that the observed reduction in platelet aggregation in preeclamptic petients might be related to the endothelial cell dysfunction seen in preeclampsia.

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Zeynep Kamil Tıp Bülteni

Alan :   Sağlık Bilimleri

Dergi Türü :   Ulusal

Metrikler
Makale : 595
Atıf : 347
Zeynep Kamil Tıp Bülteni