Abstract:

INTRODUCTION: Acinetobacter baumannii which is accepted as the most serious nosocomial pathogen has been also defined as an emerging infectious agent due to multi- drug resistant strains by recent years. Multi-drug resistant Acinetobacter baumannii isolates are linked to increased mortality and morbidity events. It is aimed to detect the predisposant factors in development of Acinetobacter baumannii infections encountered among intensive care patients. METHODS: Charts of the patients whom were detected to have Acinetobacter baumannii infection in intensive care unit between January 2014 and May 2015 have been reviewed retrospectively. The patients were grouped as MDRAB and non MDRAB infection sufferers in ICU. For both groups the recorded datas were as follows: age, sex, medical history, underlying surgical pathology, Acute Physiology and Chronic Health Evaluation 2 score( APACHE 2), presence of invase procedures(intubation, arterial, central venous lines, urinary catheters and renal replacement therapy), days in ICU, infection site, complications length of stay(LOS) in the ICU and hospital, and final outcome. RESULTS: The datas belonging to totally 92 patienst( 40 male and 52 female ) with ICU related Acinetobacter baumannii infections were reviewed in the study. The number of patients with MDRAB infections were detected as 36 and they consisted 39.1% of all cases. According to comparison of the parametres regarding ICU LOS, Hospital LOS and APACHE 2 scores,there was a significant difference between groups. When we look at the pre- ICU diagnosis of cases there was a significant relation between MDRAB infections and having DM or neoplastic diseases. We also detected a positive relation between reintubation events( more than one endotracheal intubation) and MDRAB infections. DISCUSSION AND CONCLUSION: According to the results of this retrospective study we found the factors of high APACHE 2 scores, DM and neoplastic diseases as probable predisposants in development of MDRAB infections in intensive care units

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